Innovative translational research methods

Creating patient-centred, transparent systems for surgical innovation.

Theme Surgical and orthopaedic innovation

Translational research is research aimed at translating the results of research into something that benefits humans directly. This workstream focuses on creating patient-centred, transparent systems (or methodologies) for surgical innovation.

Our research has previously identified that current systems for surgical innovation are inadequate: understanding of adverse events is insufficient, patients aren’t given enough information, and sometimes their experiences are poor.

We are working with surgeon innovators to develop, pilot and refine our methodologies to create a safe, transparent, and comprehensive innovation life cycle.

Improving how we identify innovation and incremental modifications will improve informed consent. It will also reduce harm to patients, prevent the widespread use of innovation before it is evaluated and stop inappropriate use of harmful or ineffective practices.

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Developing electronic methods for learning

As an individual surgeon gets experience of performing a procedure, they are likely to make…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

How do we stop or reduce treatments that don’t work or aren’t cost-effective?

Stopping or reducing how often a treatment is offered by the NHS is called ‘de-adoption’.

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Making trials more accessible through better patient information leaflets

Clinical trials are research projects that compare different treatments to see which one is best.

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

Developing an online platform to create accessible patient information leaflets

The National Literacy Trust says that 7.1 million people (16 per cent…

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

My Knee Plan

During this project we will ask researchers, healthcare professionals and patients to co-produce a care…

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

Joint PREP study

Hip and knee replacements are common operations for patients with osteoarthritis. It is a major…

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

Optimising the efficiency and value of burn care research

Burns affect 11 million people globally. They can lead to long-term disability and be associated…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Developing guidance for surrogate outcomes in clinical trials

SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) and CONSORT (Consolidated Standards Of Reporting Trials)…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Setting research priorities with under-served communities

This project focused on ensuring the research we conduct addresses the needs and priorities of…

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

Interviewing surgical teams to optimise new chemotherapy delivery method

Bowel, ovarian and stomach cancer often spreads (metastasises) to the lining (peritoneum) of the abdominal…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

The ALPACA study

High quality shared decision making processes that focus on the patient are an important part…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

FFLEX study

During the FFLEX study we will be looking at a new type of knee implant.

Theme Surgical and orthopaedic innovation

Workstream Novel surgical and orthopaedic techniques and devices

Improving sleep for inpatients on surgical wards

The aim of this project is to design an intervention to improve how patients on…

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

Developing a core outcome set for periprosthetic femoral fractures

A femoral fracture is a serious complication that can affect some people after they have…

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

Mapping health services available to patients waiting for joint replacement

As of April 2023, over 40 per cent of people on NHS waiting lists (a…

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

Supporting exercise before joint replacement

People waiting for a joint replacement often avoid physical activity as they believe it will…

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

Improving methods for assessing surgical site infection

The aim of this project is to explore methods to improve surgical site infection (SSI)…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Developing care for patients with dislocation after total hip replacement

The aim of this project is to develop an accessible and inclusive care pathway for…

Theme Surgical and orthopaedic innovation

Understanding how new surgical procedures and devices are introduced

The overall aim of this study is to understand and improve how innovative surgical…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Quality of life in pressurised intraperitoneal aerosolised chemotherapy

This project aims to explore the views and experiences of patients with peritoneal metastases (cancer…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Promoting inclusive research involvement through film

We know that minority ethnic communities are marginalised in healthcare and research. This means they…

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

Comparing surgical procedures for gastro-oesophageal reflux disease

The aim of this project is to compare two types of surgical procedure performed by…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Improving communication and innovation

National guidance states that patients must be fully informed if a treatment option is innovative.

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Rehabilitation for revision joint replacement

The aim of this project is to understand what rehabilitation services are currently available to…

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

REST study

Sleep and pain are strongly linked and improvements in sleep have been shown to have…

Theme Surgical and orthopaedic innovation

Workstream Interventions to improve patient outcomes after surgery

Developing replacement heart valves

The flow of blood inside the heart is controlled by valves. The largest of these…

Theme Surgical and orthopaedic innovation

Workstream Novel surgical and orthopaedic techniques and devices