Innovative translational research methods

Creating patient-centred, transparent systems for surgical innovation.

Theme Surgical and orthopaedic innovation

Translational research is research aimed at translating the results of research into something that benefits humans directly. This workstream focuses on creating patient-centred, transparent systems (or methodologies) for surgical innovation.

Our research has previously identified that current systems for surgical innovation are inadequate: understanding of adverse events is insufficient, patients aren’t given enough information, and sometimes their experiences are poor.

We are working with surgeon innovators to develop, pilot and refine our methodologies to create a safe, transparent, and comprehensive innovation life cycle.

Improving how we identify innovation and incremental modifications will improve informed consent. It will also reduce harm to patients, prevent the widespread use of innovation before it is evaluated and stop inappropriate use of harmful or ineffective practices.

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Developing electronic methods for learning

As an individual surgeon gets experience of performing a procedure, they are likely to make…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

How do we stop or reduce treatments that don’t work or aren’t cost-effective?

Stopping or reducing how often a treatment is offered by the NHS is called ‘de-adoption’.

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Optimising the efficiency and value of burn care research

Burns affect 11 million people globally. They can lead to long-term disability and be associated…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Developing guidance for surrogate outcomes in clinical trials

SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) and CONSORT (Consolidated Standards Of Reporting Trials)…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Interviewing surgical teams to optimise new chemotherapy delivery method

Bowel, ovarian and stomach cancer often spreads (metastasises) to the lining (peritoneum) of the abdominal…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

The ALPACA study

High quality shared decision making processes that focus on the patient are an important part…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Improving methods for assessing surgical site infection

The aim of this project is to explore methods to improve surgical site infection (SSI)…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Understanding how new surgical procedures and devices are introduced

The overall aim of this study is to understand and improve how innovative surgical…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Quality of life in pressurised intraperitoneal aerosolised chemotherapy

This project aims to explore the views and experiences of patients with peritoneal metastases (cancer…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Comparing surgical procedures for gastro-oesophageal reflux disease

The aim of this project is to compare two types of surgical procedure performed by…

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods

Improving communication and innovation

National guidance states that patients must be fully informed if a treatment option is innovative.

Theme Surgical and orthopaedic innovation

Workstream Innovative translational research methods