Research projects

Our projects span early stage studies such as first in human and feasibility studies to developing new research methodologies and tools. Take a look at all our projects across all our research themes and workstreams.

Using genetics to improve how drug targets are identified

Many modern drugs target very specific biological processes. When a drug is being developed,…

Theme Translational data science

Workstream Genetic evidence to prioritise intervention

Understanding how adverse childhood experiences impact anxiety-related disorders in the UK and Brazil

Adverse childhood experiences are potentially harmful experiences that can affect people both at home and…

Themes Mental health Translational data science

Workstream Genetic evidence to prioritise intervention

Exploring inflammation as a driver for post-operative complications

One in seven patients develop a serious medical problem after surgery. These types of complications…

Theme Translational data science

Workstream Omics for prediction and prognosis

Investigating new approaches to drug development using human genetics

Developing new drugs is an important part of improving our ability to treat disease. To…

Theme Translational data science

Workstream Genetic evidence to prioritise intervention

Exploring the link between obesity and heart failure using genetics

Heart failure is a condition that develops when the heart unable to pump blood around…

Theme Translational data science

Workstream Genetic evidence to prioritise intervention

Lung development in early life and respiratory diagnosis and treatment

More than 17 per cent of deaths around the world can be attributed to respiratory…

Themes Respiratory disease Translational data science

Workstream Airways and exacerbations

Can we use DNA methylation to predict disease in diverse populations?

DNA methylation is a process during which methyl groups become attached to parts of our…

Theme Translational data science

Workstream Omics for prediction and prognosis

Preventing cardiovascular events in stroke patients

Having a stroke means you are more likely to experience a subsequent cardiovascular event. Cardiovascular…

Theme Translational data science

Workstream Genetic evidence to prioritise intervention

Exploring the link between genes and cognitive decline

Cognitive decline in older adults refers to the difficulties someone may experience later in life…

Theme Translational data science

Workstream Genetic evidence to prioritise intervention