Androgen receptor variant 7 and protein interaction in prostate cancer progression
Interactions between androgen receptor variant 7 (ARV7), the forkhead box protein A1 (FOXA1) and insulin-like growth factor-2 (IGFBP-2) could potentially contribute to a more aggressive form of prostate cancer developing, according to research published in Translational Oncology. Researchers found positive associations between ARV7 and the two proteins…
NHS policies on patient’s weight and access to hip replacement surgery are inappropriate, study finds
Weight and body mass index (BMI) policies introduced by NHS commissioning groups in England are inappropriate and worsening health inequalities, according to a new study published in BMC Medicine today [13 June] that analysed nearly 490,000 hip surgeries. With one in ten people likely to need a joint replacement in…
Does intermittent fasting affect appetite?
Researchers from NIHR Bristol BRC and the School of Psychological Science in the University of Bristol found no clear difference between the effects of intermittent fasting and continuous energy restriction on hunger, fullness, a person’s desire to eat or how much they think they can eat. Findings…
Bristol part of £42 million boost for mental health research to unlock new treatments
The University of Bristol is part of a £42.7 million ‘Mental Health Mission’ announced by the Government to accelerate research into mental health conditions, including those impacting children. The research will develop radical new treatments, improve the speed and accuracy of diagnosis and increase the use of technology to free…
PhD opportunity with Bristol BRC and Health Data Research UK
The NIHR Bristol Biomedical Research Centre is working with Health Data Research UK (HDR UK) to offer a place on their prestigious Big Data for Complex Diseases PhD programme. HDR UK is funding six PhDs with leading UK universities and research organisations. Within this programme, the Bristol…
Does exercise affect how our brains respond to food cues?
A single bout of exercise increased reactivity to food cues in parts of the brain associated with attention, anticipation of reward and episodic memory, according to research published in Human Brain Mapping. Researchers from Loughborough University, University of Bristol, University of Nottingham, University of Leicester, and Waseda…
Evidence for trauma-informed organisational change programmes
Trauma-informed organisational change programmes may improve conditions for staff and patients in primary care and community mental healthcare, according to research published in Health and Social Care in the Community. Evidence was very limited and conflicting, but researchers found potential improvements to: staff readiness and sense of…
Can following the Mediterranean diet benefit breast cancer survivors?
It is possible that following a Mediterranean diet could have long-term health benefits for patients with breast cancer, according to a paper published recently in Nutrients. Researchers at the NIHR Bristol BRC and the University of Bristol found that the association between following a Mediterranean diet and…
Study shows children’s inactivity remains an issue in wake of pandemic
New research has revealed children’s physical activity in the UK has largely returned to pre-pandemic levels – but children are still more sedentary during the week. The study, led by the University of Bristol, found that by summer last year 41% of children were meeting the national recommended physical activity…